Searchable abstracts of presentations at key conferences in endocrinology

ea0068p11 | Abstracts | UKINETS2019

Can determination of radiological tumour volumes and tumour growth rates better determine response to somatostatin analogues in slowly growing neuroendocrine tumours?

Hazeldine Thomas , Braimah Fatimah , Brown Peter , Anthoney Alan

Introduction: Somatostatin analogues (SSA) are a cornerstone in the treatment of neuroendocrine tumours. Two clinical trials have defined the disease control effect of these treatments; the PROMID study of Octreotide LAR v’s placebo, median time to tumour progression (TTP) 14.2 m v’s 6.0 m, and the CLARINET study (Lanreotide v’s placebo), median progression free survival (PFS) 31 m v’s 18 m. In every day practice, however, many neuroendocrine tumours commen...